Ushering in the future of skin regeneration, SKIN functional, the science-led South African skincare brand known for its clinically effective formulations, proudly announces the launch of its most advanced innovation yet, the 10% Exosomes + 4% PDRN Bioactive Molecules Serum.
The Science of Regeneration
“This highly concentrated formulation is designed to deliver the holy grail of skin transformation, targeting collagen degradation, overproduction of melanin, reactive oxygen damage, and overall skin degradation, the root causes of visible ageing.” – Shannon Dougall, Founder of SKIN functional
At the heart of the new breakthrough product is a powerful combination of six highly purified Exosomes and revolutionary Polydeoxyribonucleotide (PDRN) derived from Bali sprout, offering a vegan, skin-restorative powerhouse suitable for Oily, Combination, Dry, and Sensitive skin types.
Exosomes: The Ingredient to Watch in 2026
Dougall explains that exosomes are nanoscale vesicles, microscopic messengers that carry proteins, RNA, and other bioactive molecules between cells. Their function? “To repair tissues, improve immune response, and enhance communication between skin cells for visible regeneration,” Dougall reveals.
This bio-intelligent activity translates to:
- Accelerated skin healing and tissue repair
- Improved skin texture and elasticity
- Visible reduction in fine lines and wrinkles
- Strengthened skin barrier and resilience
Exosome Actives include:
- Brassica Oleracea Italica (Broccoli) Vesicles
- Centella Asiatica Leaf Vesicles
- Houttuynia Cordata Leaf Vesicles
- Panax Ginseng Vesicles
- Nelumbo Nucifera Leaf Vesicles
Polydeoxyribonucleotide (PDRN): The Skin Rebuilder
PDRN is a breakthrough bioactive molecule that works by stimulating cellular repair and DNA synthesis to boost collagen production and skin regeneration. Derived from Bali sprouts, this vegan source of PDRN represents a sustainable evolution in skin science.
Clinically backed benefits include:
- Increased collagen synthesis by 185.8%
- Increased skin regeneration by 114%
- Reduced the Inflammatory factor NF-Kb (UVB-induced) by 174%
- Reduced collagen-degrading enzyme MMP (oxidative stress-induced) by up to 56%
- Reduced melanin production by 93% via inactivation of the c-AMP/PKA signalling pathway
- Reduced melanin synthesis by 37.45%
- Improved reactive oxygen scavenging by 63.98% (DPPH radical)
- Reduced MMP-1 expression by 37%
The Supporting Actives: Synergy in Motion
The serum also features the following actives that enhance its effectiveness:
- Glutathione: a potent antioxidant that defends against free radical damage, reduces hyperpigmentation, and enhances luminosity.
- Adenosine: a powerhouse anti-ageing active that restores skin’s smoothness and delivers visible wrinkle reduction while soothing sensitivity.
As such, say goodbye to collagen degradation, overproduction of melanin, skin degradation, and reactive oxygen, and say hello to stronger, smoother, more radiant skin.
A Serum That Redefines Skin Health
The 10% Exosomes + 4% PDRN Bioactive Molecules Serum is more than skincare; it’s a cellular communication system, orchestrating regeneration and balance at every level of the skin.
SKIN functional continues to lead the evolution of evidence-based skincare with formulations that deliver on their promise. As such, you can expect a visible increase in skin elasticity, diminished fine lines and wrinkles, even skin tone, luminosity, and a resilient, youthful skin barrier. Grab it here for R385.

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